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Structure of 129872-81-7
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2,4-Dichloro-5-methyl-5H-pyrrolo[3,2-d]pyrimidine serves as a key heterocyclic scaffold in medicinal chemistry, featuring a sterically hindered core with electron-deficient character. This platform integrates readily into kinase inhibitor designs and offers enhanced metabolic stability due to its fused ring system and chlorine substitutions.
2,4-Dichloro-5-methyl-5H-pyrrolo[3,2-d]pyrimidine serves as a versatile building block for the synthesis of purine-based heterocycles and kinase inhibitor scaffolds. Its dichloro substitution pattern enables selective nucleophilic displacement reactions, facilitating the construction of diverse functionalized pyrrolopyrimidines. The methyl group enhances stability and modulates electronic properties, while the scaffold exhibits excellent bench stability and compatibility with standard coupling protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: