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Structure of 1303974-46-0
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1-(Boc)-3-Fluoropiperidine-4-carboxylic acid features a fluorinated piperidine core with a Boc-protected carboxylic acid, enabling stable incorporation into peptide and small-molecule scaffolds. The electron-withdrawing fluorine enhances metabolic stability and modulates conformational flexibility. This derivative facilitates efficient synthesis of bioactive compounds under standard conditions.
1-(Boc)-3-fluoropiperidine-4-carboxylic acid serves as a versatile building block for the synthesis of fluorinated piperidine-containing scaffolds prevalent in medicinal chemistry. The Boc group provides excellent stability and ease of removal under mild acidic conditions, while the carboxylic acid functionality enables direct coupling reactions or derivatization. This compound exhibits robust bench stability and functional group tolerance, facilitating efficient incorporation into complex molecular architectures through standard peptide coupling and reductive amination protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: