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Structure of 13064-64-7
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2,5-Diiodobenzene-1,4-diol features two iodine substituents at the 2 and 5 positions flanking a pair of phenolic hydroxyl groups. This configuration enables selective coupling reactions in cross-coupling protocols, where the electron-rich diol moiety enhances reactivity while maintaining stability under standard conditions.
2,5-Diiodobenzene-1,4-diol serves as a versatile diiodinated building block for palladium-catalyzed cross-coupling reactions, enabling efficient synthesis of biaryl scaffolds under standard conditions. The phenolic hydroxyl groups provide enhanced solubility and facilitate downstream functionalization, while the iodide substituents offer high reactivity in Suzuki-Miyaura and Sonogashira coupling protocols. Bench-stable and readily purified by recrystallization, it functions as a reliable intermediate in the construction of complex heterocyclic systems and functionalized aromatic frameworks.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: