6-Chloroisoquinolin-1(2H)-one

Name: 6-Chloroisoquinolin-1(2H)-one
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 131002-09-0
Cat. No. CS-0044924
Purity≥98%
MDL No.MFCD11870518

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

6-Chloroisoquinolin-1(2H)-one|CS-0044924

Structure of 131002-09-0

Size

Price

Quantity

* Please select Quantity before adding items.

Description

6-Chloroisoquinolin-1(2H)-one is a heterocyclic scaffold featuring a chlorine substituent at the 6-position, enhancing electrophilicity at the C6 carbon. This electron-deficient core facilitates nucleophilic aromatic substitution and serves as a key building block in medicinal chemistry for targeted drug discovery. The lactam functionality provides rigidity and hydrogen-bonding capacity, improving binding affinity and metabolic stability.

Application

6-Chloroisoquinolin-1(2H)-one serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C6 position via palladium-catalyzed cross-coupling. Its stability under standard reaction conditions and compatibility with diverse nucleophiles facilitate efficient access to substituted isoquinolinones. The molecule functions as a key scaffold for constructing bioactive heterocycles and supports orthogonal transformations in multi-step synthesis.

General Information

CAS No. 131002-09-0
Cat. No. CS-0044924
Purity ≥98%
MDL No. MFCD11870518
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₆ClNO
Molecular Weight 179.60
Synonym(s) 6-chloroisoquinolin-1-ol
SMILES O=C1NC=CC2=C1C=CC(Cl)=C2

Computational Chemistry Data

TPSA 32.86
LogP 2.1815
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Isoquinoline compounds

Key Words

6-Chloroisoquinolin-1(2H)-one sigma6-Chloroisoquinolin-1(2H)-one manufacturer6-Chloroisoquinolin-1(2H)-one price6-Chloroisoquinolin-1(2H)-one structure6-Chloroisoquinolin-1(2H)-one SDSbuy 6-Chloroisoquinolin-1(2H)-one6-Chloroisoquinolin-1(2H)-one supplier6-Chloroisoquinolin-1(2H)-one uses6-Chloroisoquinolin-1(2H)-one molecular weightprice of 6-Chloroisoquinolin-1(2H)-one6-Chloroisoquinolin-1(2H)-one chemical name formula of 6-Chloroisoquinolin-1(2H)-one

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

6-Chloroisoquinolin-1(2H)-one

CAS No. 131002-09-0

Recommended Products