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Structure of 1312765-94-8
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This tetrahydroisoquinoline-based boronic acid features a tert-butoxycarbonyl-protected amine and a pendant boronic acid group, enabling direct incorporation into Suzuki-Miyaura cross-coupling reactions. The Boc handle ensures stability during purification and storage, while the electron-rich heterocyclic core supports efficient coupling under mild conditions.
(2-(Tert-butoxycarbonyl)-1,2,3,4-tetrahydroisoquinolin-6-yl)boronic acid serves as a stable, bench-ready building block for the construction of tetrahydroisoquinoline-based scaffolds in medicinal chemistry. Its boronic acid functionality enables efficient Suzuki-Miyaura cross-coupling reactions under mild conditions, while the tert-butoxycarbonyl group provides protection for the nitrogen and enhances solubility. The compound exhibits good functional group tolerance and facilitates straightforward deprotection to yield the free amine, making it well-suited for iterative synthesis of complex heterocycles and API candidates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: