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CS-W001157 4
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1-(Pyrrolidin-3-yl)-1H-imidazole dihydrochloride

  • CAS No. 1312784-53-4

  • Cat. No. CS-0624083
  • Purity≥95%
  • MDL No.MFCD09864383

*For research and further manufacturing use only, not for direct human use.

1-(Pyrrolidin-3-yl)-1H-imidazole dihydrochloride|CS-0624083

Structure of 1312784-53-4

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General Information

  • CAS No. 1312784-53-4
  • Cat. No. CS-0624083
  • Purity ≥95%
  • MDL No. MFCD09864383
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₃Cl₂N₃
  • Molecular Weight 210.11
  • Synonym(s) None
  • SMILES [H]Cl.[H]Cl.N1(C2CNCC2)C=CN=C1

Description

This imidazole derivative features a pyrrolidin-3-yl substituent that enhances solubility and modulates electronic properties, enabling effective integration into bioactive scaffolds. The dihydrochloride salt form ensures stability and facilitates handling under standard laboratory conditions.

Application

1-(Pyrrolidin-3-yl)-1H-imidazole dihydrochloride serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to imidazole-containing scaffolds. The pyrrolidin-3-yl substituent enhances solubility and modulates basicity, while the dihydrochloride salt form ensures excellent bench stability and ease of handling. It functions reliably in standard coupling reactions and facilitates the construction of complex nitrogen-rich frameworks relevant to API development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

  • TPSA   29.85
  • LogP   1.2611
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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