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Structure of 1313399-38-0
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This boronate ester integrates a sterically protected tetramethylboronate group with a planar isoindolinone core, enabling reliable cross-coupling under mild conditions. The electron-deficient carbonyl moiety enhances reactivity in Suzuki-Miyaura transformations, while the bench-stable, moisture-tolerant structure simplifies handling in synthetic workflows.
2-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoindolin-1-one serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The isoindolinone core provides structural rigidity and pharmacophoric relevance, while the tetramethylboronate group offers excellent bench stability, mild reaction conditions, and high functional group tolerance. It facilitates efficient C–C bond formation in late-stage diversification of heterocyclic scaffolds and is compatible with standard palladium-catalyzed coupling protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: