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Structure of 13138-70-0
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4-Nitrothiophene-2-carboxylic acid features a fused thiophene core bearing both a nitro group at the para position and a carboxylic acid functionality at the adjacent carbon. This combination imparts strong electron-withdrawing character and enhances reactivity in cross-coupling and cyclization processes. The molecule exhibits good bench stability and solubility in common organic solvents, facilitating straightforward integration into synthetic workflows.
4-Nitrothiophene-2-carboxylic acid serves as a versatile building block for heterocyclic synthesis, enabling direct functionalization at the thiophene core. Its nitro and carboxylic acid groups provide orthogonal reactivity for coupling reactions, metal-catalyzed transformations, and derivatization. The compound exhibits good bench stability and facilitates straightforward purification, making it suitable for iterative synthesis workflows in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: