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CS-W001157 4
Total: USD 88.00

2-Chloro-4-vinylpyrimidine,96%(stabilized with TBC)

  • CAS No. 131467-02-2

  • Cat. No. CS-0343652
  • Purity95% (stabilized with TBC)
  • MDL No.MFCD26127505

*For research and further manufacturing use only, not for direct human use.

2-Chloro-4-vinylpyrimidine,96%(stabilized with TBC)|CS-0343652

Structure of 131467-02-2

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General Information

  • CAS No. 131467-02-2
  • Cat. No. CS-0343652
  • Purity 95% (stabilized with TBC)
  • MDL No. MFCD26127505
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅ClN₂
  • Molecular Weight None
  • Synonym(s) 2-Chloro-4-ethenylpyrimidine
  • SMILES C=CC1=NC(Cl)=NC=C1

Description

2-Chloro-4-vinylpyrimidine, stabilized with TBC, features a reactive vinyl group enabling efficient coupling in cross-coupling and polymerization reactions. The electron-deficient pyrimidine core enhances reactivity, while the stabilizing additive ensures shelf stability under ambient conditions.

Application

2-Chloro-4-vinylpyrimidine (stabilized with TBC) serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its reactive vinyl and chloropyrimidine functionalities. The stabilizer TBC prevents polymerization during storage, ensuring bench stability and reliable performance in Suzuki, Stille, and Negishi coupling protocols. Its functional group tolerance and ease of purification make it ideal for constructing complex scaffolds in medicinal chemistry and materials science applications.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1760
Class : 8
Packing Group : Ⅲ
Hazard Statements : H227-H302-H314-H318
Precautionary Statements : P210-P260-P264-P270-P280-P301+P330+P331-P304+P340-P363-P370+P378-P405-P501

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Computational Chemistry Data

  • TPSA   25.78
  • LogP   1.773
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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