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Structure of 13156-04-2
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1-(tert-Butyl)azetidin-3-ol features a strained azetidine ring bearing a tertiary butyl group and a hydroxyl functionality, offering enhanced stability and solubility in polar media. This scaffold integrates readily into bioactive molecules, providing a rigid, electron-rich core for medicinal chemistry applications.
1-(tert-Butyl)azetidin-3-ol serves as a valuable chiral building block in medicinal chemistry, offering a sterically hindered azetidine core with a pendant hydroxyl group. The tert-butyl substituent enhances metabolic stability and modulates physicochemical properties. It functions reliably in nucleophilic substitution and coupling reactions, enabling access to diverse heterocyclic scaffolds. Bench-stable and amenable to purification, it facilitates efficient synthesis of bioactive molecules and API intermediates.
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GHS Pictogram :
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GHS No : GHS02
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Signal Word : Danger
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UN#: 1325
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Class : 4.1
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Packing Group : Ⅲ
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Hazard Statements : H226
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501
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Lot numbers can be found on the outside label of a product: