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Structure of 131747-45-0
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(4-Bromopyridin-2-yl)methanol features a brominated pyridine ring linked to a primary alcohol group, enabling direct functionalization in cross-coupling and derivatization workflows. The pendant hydroxymethyl moiety supports facile oxidation to aldehyde or carboxylic acid derivatives, while the electron-deficient pyridine ring enhances reactivity in nucleophilic substitution reactions under standard conditions.
(4-Bromopyridin-2-yl)methanol serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the pyridine ring and side-chain hydroxymethyl group. It functions as a key intermediate in cross-coupling reactions, particularly Suzuki-Miyaura and Negishi transformations, due to its stable bromide handle and compatible aldehyde precursor. The molecule exhibits excellent bench stability and facilitates straightforward purification, making it ideal for modular synthesis of bioactive heterocycles and pharmaceutical scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: