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Structure of 131747-61-0
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This trifluoromethylpyridylmethanol features a strategically positioned trifluoromethyl group enhancing electron-withdrawal and metabolic stability. The terminal alcohol enables straightforward functionalization, facilitating coupling reactions in medicinal chemistry. Its bench-stable, moisture-tolerant nature simplifies handling in synthetic workflows.
(2-(Trifluoromethyl)pyridin-4-yl)methanol serves as a versatile building block in medicinal chemistry, enabling efficient incorporation of a polar trifluoromethyl-pyridyl motif. Its aldehyde functionality facilitates straightforward derivatization via nucleophilic addition, oximation, or reductive amination, while the pyridine ring supports metal-catalyzed coupling reactions. The compound exhibits excellent bench stability and compatibility with common protecting group strategies, making it well-suited for multi-step synthesis and API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: