2-Phenyltetrahydro-2H-pyran-4-ol

Name: 2-Phenyltetrahydro-2H-pyran-4-ol
Brand: ChemScene
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CAS No. 132149-01-0
Cat. No. CS-0075106
Purity≥97%
MDL No.MFCD12025409

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Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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2-Phenyltetrahydro-2H-pyran-4-ol|CS-0075106

Structure of 132149-01-0

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Description

2-Phenyltetrahydro-2H-pyran-4-ol features a rigid, oxygenated heterocyclic core with a pendant phenyl group, offering enhanced stereochemical control in asymmetric synthesis. The hydroxyl at C4 enables selective derivatization, while the tetrahydropyran scaffold imparts metabolic stability and favorable solubility characteristics for use in complex molecular architectures.

Application

2-Phenyltetrahydro-2H-pyran-4-ol serves as a versatile chiral building block in synthetic organic chemistry, enabling efficient access to functionalized tetrahydropyran scaffolds. Its hydroxyl group facilitates selective derivatization, while the phenyl substituent enhances structural rigidity and metabolic stability. The compound exhibits excellent bench stability and compatibility with standard protecting group strategies, making it well-suited for multi-step synthesis workflows in medicinal chemistry and natural product analog development.

General Information

CAS No. 132149-01-0
Cat. No. CS-0075106
Purity ≥97%
MDL No. MFCD12025409
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₁H₁₄O₂
Molecular Weight None
Synonym(s) 2-phenyl-tetrahydro-2H-pyran-4-ol
SMILES OC1CC(C2=CC=CC=C2)OCC1

Computational Chemistry Data

TPSA 29.46
LogP 1.899
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Tetrahydropyran compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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2-Phenyltetrahydro-2H-pyran-4-ol

CAS No. 132149-01-0

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