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(S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine Duloxetine Impurity

  • CAS No. 132335-46-7

  • Cat. No. CS-0166049
  • Purity95+%
  • MDL No.MFCD08458281

*For research and further manufacturing use only, not for direct human use.

(S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine  Duloxetine Impurity|CS-0166049

Structure of 132335-46-7

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General Information

  • CAS No. 132335-46-7
  • Cat. No. CS-0166049
  • Purity 95+%
  • MDL No. MFCD08458281
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₉H₂₁NOS
  • Molecular Weight 311.44
  • Synonym(s) S-(+)-N,N-dimethyl-3-(1-naphthlenyloxy)-3-(2-thienyl)-propanamine
  • SMILES CN(C)CC[C@H](OC1=C2C=CC=CC2=CC=C1)C3=CC=CS3

Synthesis

  • Route1

    References

    • WO2008/93360 A2, ; Page/Page column 14-15 ;
  • Route2
    • null|null
      878757-07-4
    • ~%
    • (S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine  Duloxetine Impurity|CS-0166049
      132335-46-7

    References

    • WO2006/27798 A2, ; Page/Page column 19; 20 ;
  • Route3
    • null|null
      885601-08-1
    • ~%
    • (S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine  Duloxetine Impurity|CS-0166049
      132335-46-7

    References

    • EP1857451 A1, ; Page/Page column 5 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS08
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H361
Precautionary Statements : P280-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.47
  • LogP   4.9731
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   6

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