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CS-W001157 4
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(2R-trans)-1-(tert-Butoxycarbonyl)-4-cyanopyrrolidine-2-carboxylic acid

  • CAS No. 132622-80-1

  • Cat. No. CS-0433609
  • Molecule weight240.26
  • Purity≥95%
  • MDL No.MFCD14582689

*For research and further manufacturing use only, not for direct human use.

(2R-trans)-1-(tert-Butoxycarbonyl)-4-cyanopyrrolidine-2-carboxylic acid|CS-0433609

Structure of 132622-80-1

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General Information

  • CAS No. 132622-80-1
  • Cat. No. CS-0433609
  • Purity ≥95%
  • MDL No. MFCD14582689
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₆N₂O₄
  • Molecular Weight 240.26
  • Synonym(s) (2R,4S)-1-(tert-butoxycarbonyl)-4-cyanopyrrolidine-2-carboxylic acid
  • SMILES O=C(N1[C@@H](C(O)=O)C[C@H](C#N)C1)OC(C)(C)C

Synthesis

  • Route1
    • null|null
      132623-07-5
    • ~97%
    • (2R-trans)-1-(tert-Butoxycarbonyl)-4-cyanopyrrolidine-2-carboxylic acid|CS-0433609
      132622-80-1

    References

    • Webb, Thomas R.; Eigenbrot, Charles Journal of Organic Chemistry, 1991 , vol. 56, # 9 p. 3009 - 3016
  • Route2
    • (2R,4R)-1-tert-Butyl 2-ethyl 4-hydroxypyrrolidine-1,2-dicarboxylate|CS-0434697
      77450-00-1
    • ~%
    • (2R-trans)-1-(tert-Butoxycarbonyl)-4-cyanopyrrolidine-2-carboxylic acid|CS-0433609
      132622-80-1

    References

    • Webb, Thomas R.; Eigenbrot, Charles Journal of Organic Chemistry, 1991 , vol. 56, # 9 p. 3009 - 3016

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   90.63
  • LogP   1.22018
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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