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Structure of 132682-77-0
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Diphenyl(6-methyl-2-pyridyl)phosphine features a sterically hindered pyridyl group that enhances stability and modulates electronic properties. This bench-stable ligand integrates readily into palladium-catalyzed cross-coupling reactions, offering improved efficiency in challenging transformations.
Diphenyl(6-methyl-2-pyridyl)phosphine serves as a robust, bench-stable ligand in palladium-catalyzed cross-coupling reactions. Its pyridyl moiety enhances electron density at phosphorus, improving catalyst activity and stability in Suzuki-Miyaura and Stille couplings. The 6-methyl substituent provides steric tuning and improves solubility, facilitating purification and scalability. This ligand is particularly effective in challenging coupling scenarios involving sterically hindered or electron-deficient substrates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: