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CS-W001157 4
Total: USD 88.00

2,6-Dichloropurine riboside

  • CAS No. 13276-52-3

  • Cat. No. CS-W005824
  • Purity≥95%
  • MDL No.MFCD03411342

*For research and further manufacturing use only, not for direct human use.

2,6-Dichloropurine riboside|CS-W005824

Structure of 13276-52-3

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General Information

  • CAS No. 13276-52-3
  • Cat. No. CS-W005824
  • Purity ≥95%
  • MDL No. MFCD03411342
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₀Cl₂N₄O₄
  • Molecular Weight 321.12
  • Synonym(s) None
  • SMILES O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C=NC3=C2N=C(Cl)N=C3Cl

Description

2,6-Dichloropurine riboside features a purine core with chlorine substituents at the 2- and 6-positions, enhancing metabolic stability. The ribose moiety enables direct incorporation into nucleic acid analogs, supporting applications in antiviral and anticancer research. This compound serves as a key building block for modified nucleosides.

Application

2,6-Dichloropurine riboside serves as a key building block for nucleoside analogs, enabling efficient synthesis of purine-based scaffolds through standard glycosylation and functionalization protocols. Its dichloro substitution pattern enhances regioselectivity in downstream coupling reactions, while the ribose moiety supports facile derivatization and incorporation into biologically relevant heterocycles. Bench-stable and compatible with common protecting group strategies, it facilitates streamlined access to potential antiviral and anticancer leads via established medicinal chemistry workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   113.52
  • LogP   -0.2554
  • H_Acceptors   8
  • H_Donors   3
  • Rotatable_Bonds   2

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