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Structure of 132865-53-3
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(5-Chloro-6-methoxypyridin-3-yl)methanol features a pyridine core functionalized with chlorine and methoxy groups at positions 5 and 6, respectively, and a reactive hydroxymethyl moiety at position 3. This configuration enables direct coupling or derivatization in synthetic workflows requiring electron-deficient heterocyclic scaffolds with orthogonal handles. The molecule exhibits bench-stable behavior under standard conditions and supports efficient integration into medicinal chemistry campaigns targeting kinase inhibitors and bioactive heterocycles.
(5-Chloro-6-methoxypyridin-3-yl)methanol serves as a versatile building block in medicinal chemistry, enabling efficient access to pyridine-based scaffolds. Its pendant hydroxymethyl group facilitates derivatization via oxidation, protection, or coupling reactions, while the chloro and methoxy substituents provide orthogonal reactivity for further functionalization. The compound exhibits excellent bench stability and compatibility with standard synthetic protocols, making it well-suited for modular synthesis of API candidates and heterocyclic intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H320-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: