Lot numbers can be found on the outside label of a product:
H-Lys(Boc)-OtBu.HCl
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CAS No. 13288-57-8
- Cat. No. CS-W005295
- Purity≥95%
- MDL No.MFCD00038899
*For research and further manufacturing use only, not for direct human use.
Structure of 13288-57-8
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General Information
- CAS No. 13288-57-8
- Cat. No. CS-W005295
- Purity ≥95%
- MDL No. MFCD00038899
- Storage 4°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₅H₃₁ClN₂O₄
- Molecular Weight 338.87
- Synonym(s) None
- SMILES N[C@@H](CCCCNC(OC(C)(C)C)=O)C(OC(C)(C)C)=O.[H]Cl
Description
H-Lys(Boc)-OtBu·HCl features a fully protected lysine residue with orthogonal Boc and OtBu groups, enabling selective deprotection during peptide synthesis. This bench-stable derivative simplifies Nα- and side-chain functionalization workflows while maintaining high reactivity under standard coupling conditions.
Application
H-Lys(Boc)-OtBu·HCl serves as a robust, bench-stable building block for peptide synthesis, offering orthogonal protection of both the α-amino and side-chain ε-amino groups. The Boc group ensures efficient removal under mild acidic conditions, while the OtBu ester enables straightforward deprotection and derivatization. Its compatibility with standard coupling protocols and ease of purification make it ideal for constructing complex peptides and heterocyclic scaffolds in medicinal chemistry workflows.
Synthesis
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Route1
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7750-44-9 - ~%
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In-stock
13288-57-8
References
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Recueil des Travaux Chimiques des Pays Bas, , vol. 102, # 11 p. 469 - 474
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Route2
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In-stock
2389-60-8 - ~%
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In-stock
13288-57-8
References
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Recueil des Travaux Chimiques des Pays Bas, , vol. 102, # 11 p. 469 - 474
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Route3
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In-stock
36805-97-7 - ~%
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In-stock
13288-57-8
References
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Recueil des Travaux Chimiques des Pays Bas, , vol. 102, # 11 p. 469 - 474
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Safety Information
Download SDS|
GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Quality Control
Computational Chemistry Data
- TPSA 90.65
- LogP 2.7722
- H_Acceptors 5
- H_Donors 2
- Rotatable_Bonds 6
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Key Words
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