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Structure of 1328882-30-9
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This boronate moiety features a cyano group ortho to the boronic acid, enhancing electronic withdrawal and stabilizing the boron center. The methyl substituent provides steric and electronic tuning, improving reactivity in Suzuki-Miyaura couplings under standard conditions.
(2-Cyano-4-methylphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient construction of biaryl scaffolds under mild conditions. Its cyano and methyl groups confer enhanced stability and modulate electronic properties, while the boronic acid functionality facilitates reliable cross-coupling with aryl halides and triflates. The compound exhibits good bench stability, ease of purification, and compatibility with diverse functional groups, making it well-suited for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: