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CS-W001157 4
Total: USD 88.00

(R)-1-Boc-3-cyanopyrrolidine

  • CAS No. 132945-76-7

  • Cat. No. CS-W009075
  • Purity≥97%
  • MDL No.MFCD05863904

*For research and further manufacturing use only, not for direct human use.

(R)-1-Boc-3-cyanopyrrolidine|CS-W009075

Structure of 132945-76-7

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General Information

  • CAS No. 132945-76-7
  • Cat. No. CS-W009075
  • Purity ≥97%
  • MDL No. MFCD05863904
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₆N₂O₂
  • Molecular Weight 196.25
  • Synonym(s) tert-Butyl-(3R)-3-cyanpyrrolidin-1-carboxylat
  • SMILES N#C[C@H]1CN(CC1)C(OC(C)(C)C)=O

Synthesis

  • Route1
    • null|null
      773837-37-9
    • In-stock
      (S)-tert-Butyl 3-((methylsulfonyl)oxy)pyrrolidine-1-carboxylate|CS-0154771
      132945-75-6
    • ~69%
    • (R)-1-Boc-3-cyanopyrrolidine|CS-W009075
      132945-76-7

    References

    • GLAXOSMITHKLINE LLC; DOCK, Steven, Thomas; MCSHERRY, Allison, K.; MOORE, Michael, Lee; RIDGERS, Lance, Howard; PARRISH, Cynthia, Ann Patent: WO2013/28445 A1, 2013 ; Location in patent: Page/Page column 51 ;
  • Route2

    References

    • ASTRAZENECA AB; ASTRAZENEKA UK LIMITED Patent: WO2005/26156 A1, 2005 ; Location in patent: Page/Page column 117 ; WO 2005/026156 A1
  • Route3

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 10, # 21 p. 2417 - 2419

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   53.33
  • LogP   1.76698
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

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