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Structure of 133228-21-4
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N,N-Dimethyl-1H-pyrazole-1-sulfonamide features a pyrazole core bearing a sulfonamide group and two methyl substituents, delivering enhanced solubility and metabolic stability. This scaffold integrates readily into medicinal chemistry libraries, offering a polar yet lipophilic moiety for probing target engagement in kinase and enzyme inhibition studies.
N,N-Dimethyl-1H-pyrazole-1-sulfonamide serves as a versatile sulfonamide building block in medicinal chemistry, enabling the construction of heterocyclic scaffolds through established coupling and functionalization protocols. Its dimethylamino group enhances solubility and provides a handle for further derivatization, while the pyrazole core offers robust stability and orthogonal reactivity. The compound exhibits favorable bench stability and ease of purification, making it well-suited for iterative synthesis campaigns in API development and target-oriented discovery.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: