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Structure of 1332392-76-3
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5-Bromo-2-chloro-3-(difluoromethyl)pyridine features a sterically constrained pyridine core bearing bromo, chloro, and difluoromethyl substituents at strategic positions. This electron-deficient heterocycle integrates readily into cross-coupling reactions, enabling efficient access to advanced pharmaceutical intermediates and functionalized materials under standard conditions.
5-Bromo-2-chloro-3-(difluoromethyl)pyridine serves as a versatile building block for constructing bioactive heterocycles, enabling palladium-catalyzed cross-coupling reactions with high functional group tolerance. The difluoromethyl group enhances metabolic stability and modulates lipophilicity, while the bromo and chloro substituents facilitate sequential functionalization. Its bench-stable nature and compatibility with standard synthetic workflows make it ideal for medicinal chemistry and process development applications.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2810
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H311-H331
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501
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Lot numbers can be found on the outside label of a product: