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Structure of 1333996-55-6
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tert-Butyl 4-bromo-3-cyano-5,6-dihydro-1,7-naphthyridine-7(8H)-carboxylate features a sterically shielded tert-butyl ester and a bromo-substituted naphthyridine core, enabling direct functionalization in late-stage diversification. The electron-deficient ring system supports palladium-catalyzed cross-coupling reactions under standard conditions. This bench-stable intermediate integrates readily into complex heterocyclic architectures for medicinal chemistry applications.
tert-Butyl 4-bromo-3-cyano-5,6-dihydro-1,7-naphthyridine-7(8H)-carboxylate serves as a versatile building block for the synthesis of functionalized naphthyridine scaffolds. The bromo and cyano groups enable palladium-catalyzed cross-coupling and nucleophilic substitution reactions, respectively, while the tert-butyl ester facilitates selective deprotection under mild acidic conditions. Its stability and compatibility with standard synthetic protocols make it well-suited for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: