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Structure of 1337880-58-6
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tert-Butyl 6-hydroxy-1H-indazole-1-carboxylate features a bench-stable indazole core with a strategically positioned hydroxyl group enabling downstream functionalization. The tert-butyl ester facilitates purification and protection of the carboxylic acid, while the electron-rich heterocycle supports transition metal-catalyzed coupling reactions. This compound serves as a key intermediate in the synthesis of bioactive indazole derivatives.
tert-Butyl 6-hydroxy-1H-indazole-1-carboxylate serves as a versatile building block for indazole-based scaffolds, enabling straightforward functionalization at the C6 position. The hydroxyl group facilitates derivatization via esterification, etherification, or transition-metal-catalyzed coupling reactions. Its tert-butyl carbamate handle provides stability and ease of removal under mild acidic conditions, supporting efficient synthesis of biologically relevant indazole derivatives in medicinal chemistry and process development workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: