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CS-W001157 4
Total: USD 88.00

2-Chloro-6-iodobenzoic acid

  • CAS No. 13420-63-8

  • Cat. No. CS-W019356
  • Purity≥96%
  • MDL No.MFCD06808823

*For research and further manufacturing use only, not for direct human use.

2-Chloro-6-iodobenzoic acid|CS-W019356

Structure of 13420-63-8

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General Information

  • CAS No. 13420-63-8
  • Cat. No. CS-W019356
  • Purity ≥96%
  • MDL No. MFCD06808823
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄ClIO₂
  • Molecular Weight 282.46
  • Synonym(s) None
  • SMILES O=C(O)C1=C(I)C=CC=C1Cl

Application

2-Chloro-6-iodobenzoic acid serves as a versatile building block for palladium-catalyzed cross-coupling reactions, enabling efficient C–C bond formation in the synthesis of biaryl scaffolds. The ortho-chloro and meta-iodo substituents offer orthogonal reactivity, facilitating sequential functionalization. Its bench-stable crystalline form simplifies handling and purification, making it well-suited for medicinal chemistry and process development workflows.

Synthesis

  • Route1
    • 2-Chlorobenzoic acid Mesalazine  Impurity|CS-0229161
      118-91-2
    • ~87%
    • In-stock
      2-Chloro-6-iodobenzoic acid|CS-W019356
      13420-63-8

    References

    • Mei, Tian-Sheng; Giri, Ramesh; Maugel, Nathan; Yu, Jin-Quan Angewandte Chemie - International Edition, 2008 , vol. 47, # 28 p. 5215 - 5219
  • Route2

    References

    • Uchikawa, Osamu; Mitsui, Keita; Asakawa, Akiko; Morimoto, Shigeru; Yamamoto, Masataka; Kimura, Hiroyuki; Moriya, Takeo; Mizuno, Masahiro Patent: US2003/187014 A1, 2003 ;
  • Route3
    • null|null
      100960-33-6
    • ~%
    • In-stock
      2-Chloro-6-iodobenzoic acid|CS-W019356
      13420-63-8

    References

    • Pelz,K. et al. Collection of Czechoslovak Chemical Communications, 1968 , vol. 33, # 6 p. 1852 - 1872

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H319
Precautionary Statements : P264-P270-P280-P330-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.6428
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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