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CS-W001157 4
Total: USD 88.00

Acid-C2-PEG4-C2-NHS ester

  • CAS No. 1343476-41-4

  • Cat. No. CS-0107924
  • Purity≥98%
  • MDL No.MFCD27952888
  • HazMat Fee +

    HazMat Fee

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Acid-C2-PEG4-C2-NHS ester|CS-0107924

Structure of 1343476-41-4

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Description

Acid-C2-PEG4-C2-NHS ester is a bifunctional linker featuring a carboxylic acid terminus and a reactive NHS ester, enabling site-specific conjugation to primary amines. The C2-PEG4-C2 spacer provides enhanced solubility and controlled distance between functional groups, facilitating efficient bioconjugation in aqueous environments. This reagent streamlines the synthesis of protein-polymer hybrids and targeted delivery systems.

Application

Acid-C2-PEG4-C2-NHS ester serves as a versatile bifunctional linker for conjugating carboxyl-containing biomolecules to amine-functionalized surfaces or probes. The PEG4 spacer provides enhanced solubility and reduced steric hindrance, while the NHS ester enables efficient coupling under physiological conditions. This reagent facilitates site-specific bioconjugation with excellent stability in aqueous media and is well-suited for antibody-drug conjugate development, protein labeling, and solid-phase synthesis workflows.

General Information

  • CAS No. 1343476-41-4
  • Cat. No. CS-0107924
  • Purity ≥98%
  • MDL No. MFCD27952888
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₈H₂₉NO₁₁
  • Molecular Weight 435.42
  • Synonym(s) None
  • SMILES O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCOCCC(O)=O

Computational Chemistry Data

  • TPSA   147.13
  • LogP   -0.4586
  • H_Acceptors   10
  • H_Donors   1
  • Rotatable_Bonds   19

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

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