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Structure of 134450-56-9
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4,5-Difluorophthalonitrile features two fluorine atoms at the 4 and 5 positions of the phthalonitrile core, enhancing electron-withdrawal and improving reactivity in nucleophilic aromatic substitution. This bench-stable compound integrates readily into heterocyclic systems, enabling efficient synthesis of fluorinated pharmaceutical intermediates and advanced materials.
4,5-Difluorophthalonitrile serves as a versatile building block in synthetic organic chemistry, enabling the construction of fluorinated heterocycles via cyclization reactions. Its dual nitrile groups and electron-deficient aromatic core facilitate nucleophilic aromatic substitution and transition-metal-catalyzed coupling processes. The molecule exhibits good bench stability and functional group tolerance, making it well-suited for iterative synthesis in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301+H311+H331-H315-H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501
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Lot numbers can be found on the outside label of a product: