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Structure of 134589-59-6
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3-Chloro-1H-pyrazole-4-carboxylic acid features a pyrazole core bearing a chlorine substituent at the 3-position and a carboxylic acid group at the 4-position, enabling direct integration into bioactive scaffolds. This electron-deficient heterocycle offers enhanced reactivity in coupling reactions and serves as a key building block for pharmaceutical intermediates.
3-Chloro-1H-pyrazole-4-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling direct incorporation into bioactive heterocycles via amidation, esterification, or coupling reactions. Its chlorine substituent enhances electrophilicity for further functionalization, while the carboxylic acid group facilitates conjugation and salt formation. The compound exhibits good bench stability and compatibility with standard purification techniques, making it suitable for scalable synthesis of pyrazole-based scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: