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Structure of 1346555-56-3
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4-Bromo-3-fluoro-1H-pyrazole is a heterocyclic building block featuring complementary halogen substituents that enable diverse cross-coupling transformations. The bromine at the 4-position facilitates palladium-catalyzed reactions, while the fluorine at the 3-position enhances electronic modulation and metabolic stability in medicinal chemistry applications. This scaffold integrates readily into bioactive molecules under standard conditions.
4-Bromo-3-fluoro-1H-pyrazole serves as a versatile building block for the synthesis of functionalized heterocycles and pharmaceutical intermediates. Its complementary halogenation pattern enables palladium-catalyzed cross-coupling reactions with high regioselectivity, while the fluorine atom enhances metabolic stability and modulates electronic properties. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for scalable synthetic workflows in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P501
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Lot numbers can be found on the outside label of a product: