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Structure of 134856-58-9
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This boronate moiety integrates a para-iodophenyl group with a trimethylsilyl-protected alkyne, enabling efficient copper-catalyzed coupling under standard conditions. The silyl-protected alkyne offers enhanced stability and moisture tolerance, simplifying handling in synthetic workflows.
((4-Iodophenyl)ethynyl)trimethylsilane serves as a versatile building block in palladium-catalyzed coupling reactions, enabling efficient access to conjugated aryl alkynes. The trimethylsilyl group provides excellent bench stability and facilitates purification, while the iodide functions as a reliable coupling handle in Sonogashira, Suzuki-Miyaura, and Stille reactions. Its compatibility with diverse functional groups makes it a practical choice for constructing complex molecular architectures in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H319-H413
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Precautionary Statements : P264-P273-P280-P501
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Lot numbers can be found on the outside label of a product: