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CS-W001157 4
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((2R,3R,5R)-3-(benzoyloxy)-4,4-difluoro-5-((methylsulfonyl)oxy)tetrahydrofuran-2-yl)methyl benzoate

  • CAS No. 134877-42-2

  • Cat. No. CS-0357062
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

((2R,3R,5R)-3-(benzoyloxy)-4,4-difluoro-5-((methylsulfonyl)oxy)tetrahydrofuran-2-yl)methyl benzoate|CS-0357062

Structure of 134877-42-2

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General Information

  • CAS No. 134877-42-2
  • Cat. No. CS-0357062
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₀H₁₈F₂O₈S
  • Molecular Weight 456.41
  • Synonym(s) 3,5-Bis(benzoyl)-1-methanesulfonyloxy-2-deoxy-2,2-difluororibose(α-form)
  • SMILES CS(=O)(=O)O[C@@H]1C([C@@H]([C@@H](COC(=O)C2=CC=CC=C2)O1)OC(=O)C3=CC=CC=C3)(F)F

Synthesis

  • Route1

    References

    • Quintiliani, Maurizio; Persoons, Leentje; Solaroli, Nicola; Karlsson, Anna; Andrei, Graciela; Snoeck, Robert; Balzarini, Jan; McGuigan, Christopher Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 14 p. 4338 - 4345
  • Route2

    References

    • Synthesis, , # 6 p. 565 - 570

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   105.2
  • LogP   2.4054
  • H_Acceptors   8
  • H_Donors   0
  • Rotatable_Bonds   7

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