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Structure of 134892-19-6
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Tert-butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propanoate delivers a stable, bench-ready boronate ester for Suzuki-Miyaura cross-coupling. The tetramethyl-substituted dioxaborolane enhances shelf life and resistance to protodeboronation, while the tert-butyl ester facilitates orthogonal protection in complex synthesis. This reagent integrates seamlessly into late-stage functionalization workflows under mild conditions.
Tert-butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propanoate serves as a stable, bench-ready boron building block for Suzuki-Miyaura cross-coupling reactions. The sterically protected boronate ester exhibits excellent functional group tolerance and facilitates efficient C–C bond formation under mild conditions. Its tert-butyl ester moiety enables straightforward conversion to the corresponding carboxylic acid or amide during late-stage diversification, making it a practical tool for constructing bioactive scaffolds in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: