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Structure of 13493-47-5
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N-(2-Formylphenyl)acetamide features a strategically positioned formyl group ortho to the amide linkage, enabling direct participation in cyclization reactions. This arrangement facilitates rapid access to functionalized benzimidazoles under mild conditions. The compound exhibits excellent solubility in common organic solvents and maintains stability during standard bench handling.
N-(2-Formylphenyl)acetamide serves as a versatile building block in medicinal chemistry, enabling efficient access to benzimidazole and benzoxazole scaffolds via cyclization reactions. The ortho-formyl group facilitates directed metalation and acts as a key electrophilic handle for nucleophilic addition, while the acetamide moiety provides moderate stability and favorable solubility. Its bench-stable nature and compatibility with standard coupling and functionalization protocols make it well-suited for multi-step synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: