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CS-W001157 4
Total: USD 88.00

1,2,4-Trimethoxybenzene

  • CAS No. 135-77-3

  • Cat. No. CS-W017803
  • Molecule weight168.19
  • Purity≥95%
  • MDL No.MFCD00008360

*For research and further manufacturing use only, not for direct human use.

1,2,4-Trimethoxybenzene|CS-W017803

Structure of 135-77-3

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General Information

  • CAS No. 135-77-3
  • Cat. No. CS-W017803
  • Purity ≥95%
  • MDL No. MFCD00008360
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₂O₃
  • Molecular Weight 168.19
  • Synonym(s) None
  • SMILES COC(C(OC)=C1)=CC=C1OC

Description

t-Butoxycarbonyl-PEG4-sulfonic acid is a PEG linker containing a t-butyl protecting group and sulfonic acid moiety. t-bytl can be removed under acidic conditions. Sulfonic acid groups can participate in esterification, halogenation and replacement reactions. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.

Synthesis

  • Route1

    References

    • Goossen, Lukas J.; Linder, Christophe; Rodriguez, Nuria; Lange, Paul P.; Fromm, Andreas Chemical Communications, 2009 , # 46 p. 7173 - 7175
  • Route2
    • 1,2,4-Trihydroxybenzene Paroxetine Impurity|CS-0214046
      533-73-3
    • null|null
      77-78-1
    • ~99%
    • In-stock
      1,2,4-Trimethoxybenzene|CS-W017803
      135-77-3

    References

    • Kamino, Shinichiro; Ichikawa, Hayato; Wada, Shun-ichi; Horio, Yuka; Usami, Yoshihide; Yamaguchi, Takako; Koda, Toshiki; Harada, Aki; Shimanuki, Kazusa; Arimoto, Masao; Doi, Mitsunobu; Fujita, Yoshikazu Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 15 p. 4380 - 4384
  • Route3
    • In-stock
      3,4-Dimethoxyphenol|CS-B1823
      2033-89-8
    • null|null
      74-88-4
    • ~97%
    • In-stock
      1,2,4-Trimethoxybenzene|CS-W017803
      135-77-3

    References

    • Alves, Ana P. L.; Junior, Jose Augusto B. C.; Slana, Glaucia B. A.; Cardoso, Jari N.; Wang, Qiang; Lopes, Rosangela S. C.; Lopes, Claudio C. Synthetic Communications, 2009 , vol. 39, # 20 p. 3693 - 3709

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   27.69
  • LogP   1.7124
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   3

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