1-(tert-Butyl) 4-methyl 4-(cyanomethyl)piperidine-1,4-dicarboxylate

Name: 1-(tert-Butyl) 4-methyl 4-(cyanomethyl)piperidine-1,4-dicarboxylate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1350475-42-1
Cat. No. CS-0018090
Purity≥95%
MDL No.MFCD18072615

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-(tert-Butyl) 4-methyl 4-(cyanomethyl)piperidine-1,4-dicarboxylate|CS-0018090

Structure of 1350475-42-1

Size

Price

Quantity

* Please select Quantity before adding items.

Description

1-(tert-Butyl) 4-methyl 4-(cyanomethyl)piperidine-1,4-dicarboxylate features a sterically shielded tert-butyl group and a nitrile-bearing side chain, enabling selective functionalization in complex molecule synthesis. The piperidine core offers tunable basicity and conformational stability under standard bench conditions. This scaffold integrates readily into bioactive compound libraries via orthogonal transformations.

Application

1-(tert-Butyl) 4-methyl 4-(cyanomethyl)piperidine-1,4-dicarboxylate serves as a versatile building block for piperidine-based scaffolds in medicinal chemistry. The cyanomethyl group enables subsequent transformations such as nitrile reduction or cyclization, while the tert-butyl and methyl ester functionalities offer orthogonal protection and synthetic flexibility. Its bench stability and compatibility with standard coupling and deprotection protocols facilitate efficient synthesis of complex heterocyclic compounds.

General Information

CAS No. 1350475-42-1
Cat. No. CS-0018090
Purity ≥95%
MDL No. MFCD18072615
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₄H₂₂N₂O₄
Molecular Weight 282.34
Synonym(s) 1-tert-butyl 4-methyl 4-(cyanomethyl)piperidine-1,4-dicarboxylate
SMILES O=C(N1CCC(C(OC)=O)(CC#N)CC1)OC(C)(C)C

Computational Chemistry Data

TPSA 79.63
LogP 2.09038
H_Acceptors 5
H_Donors 0
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Cyanide/Nitrile

Building Blocks Functional Group Ester

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Key Words

1350475-42-1 sigma1350475-42-1 manufacturer1350475-42-1 price1350475-42-1 structure1350475-42-1 SDSbuy 1350475-42-11350475-42-1 supplier1350475-42-1 uses1350475-42-1 molecular weightprice of 1350475-42-11350475-42-1 chemical name formula of 1350475-42-1

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

1-(tert-Butyl) 4-methyl 4-(cyanomethyl)piperidine-1,4-dicarboxylate

CAS No. 1350475-42-1

Recommended Products