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Structure of 13519-90-9
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4-Fluoroisophthalonitrile features a fluorinated aromatic ring with two nitrile groups in a para relationship, enabling robust coupling reactions. The electron-withdrawing fluorine substituent enhances reactivity in nucleophilic substitutions and facilitates integration into advanced heterocycles. This bench-stable compound serves as a key building block for pharmaceutical intermediates and functional materials.
4-Fluoroisophthalonitrile serves as a versatile building block in synthetic organic chemistry, enabling the construction of fluorinated aromatic scaffolds through palladium-catalyzed cross-coupling and nucleophilic substitution reactions. Its dual nitrile groups and ortho-fluorine substituent provide high functional group tolerance and facilitate downstream derivatization in medicinal chemistry and materials science applications. The compound exhibits excellent bench stability and is readily purified by recrystallization, making it well-suited for scalable synthesis workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: