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Structure of 1353011-74-1
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Ald-Ph-amido-PEG4-C2-NHS ester features a reactive NHS ester group paired with a PEG4 spacer and a terminal aldehyde for site-specific conjugation. This bifunctional reagent enables efficient coupling to amine-containing biomolecules under physiological conditions, followed by selective oxime ligation. The hydrophilic PEG chain minimizes non-specific binding, enhancing solubility and stability in aqueous environments.
Ald-Ph-amido-PEG4-C2-NHS ester serves as a versatile bifunctional linker for protein conjugation and bioconjugate synthesis. The aldehyde group enables site-specific coupling via reductive amination, while the NHS ester facilitates efficient amine-reactive attachment. The PEG4 spacer provides enhanced solubility and reduced steric hindrance, and the phenylamido moiety offers improved hydrolytic stability compared to standard amides. This reagent functions reliably in aqueous buffers at physiological pH, enabling robust conjugation workflows with minimal aggregation.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: