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Structure of 135325-18-7
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Methyl 2-[4-(trifluoromethyl)phenyl]acetate features a trifluoromethyl-substituted aryl group that imparts enhanced electron-withdrawal and metabolic stability. This ester integrates readily into synthetic sequences requiring hydrophobic, electron-deficient aromatic components. The methyl ester moiety enables straightforward derivatization under standard conditions.
Methyl 2-[4-(trifluoromethyl)phenyl]acetate serves as a versatile building block in medicinal chemistry, enabling the synthesis of biologically active compounds through standard functional group transformations. The trifluoromethyl aryl moiety imparts enhanced metabolic stability and lipophilicity, while the ester functionality facilitates selective derivatization. Its bench-stable nature and compatibility with common coupling and reduction protocols make it ideal for modular scaffold construction in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H320-H335
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Precautionary Statements : P264-P270-P330
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Lot numbers can be found on the outside label of a product: