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Structure of 135450-23-6
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6-(Chloromethyl)-2-cyanopyridine features a reactive chloromethyl group flanked by an electron-deficient pyridine ring and a nitrile moiety, enabling selective functionalization in late-stage diversification. This scaffold integrates readily into complex molecular architectures under mild conditions.
6-(Chloromethyl)-2-cyanopyridine serves as a versatile bifunctional building block in medicinal chemistry, enabling efficient installation of both nitrile and chloromethyl handles. The chloromethyl group facilitates nucleophilic substitution reactions, while the cyano functionality supports hydrolysis, reduction, or cyclization pathways. Its bench-stable nature and compatibility with diverse reaction conditions make it well-suited for constructing heterocyclic scaffolds and peptide conjugates in iterative synthesis workflows.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H314
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Precautionary Statements : P264-P271-P280-P301+P330+P331-P304+P340-P363-P501
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Lot numbers can be found on the outside label of a product: