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Structure of 1356019-51-6
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Building block for introduction of cysteinyl residues by Fmoc SPPS. The t-Buthio group can be selectively removed using thiols [1] or tributylphosphine[2,3]. This protecting group is stable to TFA if thiol scavengers are not used. Associated Protocols and Technical ArticlesCleavage and Deprotection Protocols for Fmoc SPPSFmoc SPPS of Cysteine-Containing PeptidesLiterature references[1] U. Weber & P. Hartter (1970) Hoppe-Seylers Z. Physiol. Chem., 351, 1384. [2] U. T. Ruegg & H. G. Gattner (1975) Hoppe-Seylers Z. Physiol. Chem., 356, 1527. [3] N. J. C. Beekman, et al. (1997) J. Peptide Res., 50, 357.
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