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Structure of 1357351-86-0
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tert-Butyl 1-(hydroxymethyl)-2-oxa-5-azabicyclo[2.2.1]heptane-5-carboxylate features a rigid, bridged heterocyclic scaffold with a pendant hydroxymethyl group and a bench-stable tert-butyl ester. This configuration enables selective functionalization and incorporation into complex molecular architectures, particularly in the synthesis of constrained bioactive compounds and macrocyclic scaffolds.
tert-Butyl 1-(hydroxymethyl)-2-oxa-5-azabicyclo[2.2.1]heptane-5-carboxylate serves as a versatile bicyclic building block for medicinal chemistry, enabling efficient access to constrained heterocyclic scaffolds. The pendant hydroxymethyl group facilitates downstream functionalization via oxidation or derivatization, while the protected carboxylic acid supports orthogonal transformations. Its bench-stable nature and compatibility with standard coupling and reduction protocols make it well-suited for modular synthesis of bioactive molecules.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362+P364
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Lot numbers can be found on the outside label of a product: