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Structure of 13603-25-3
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3-Benzylpiperidine features a benzyl-substituted piperidine core, delivering enhanced lipophilicity and metabolic stability. This scaffold integrates readily into bioactive molecules, serving as a key pharmacophore in CNS-targeted compounds. The benzylic position enables efficient functionalization, while the nitrogen center supports salt formation for improved solubility and handling.
3-Benzylpiperidine serves as a versatile scaffold in medicinal chemistry, enabling the construction of bioactive heterocycles through standard functionalization protocols. Its benzylic position facilitates oxidation, halogenation, and cross-coupling reactions, while the piperidine core offers favorable basicity and metabolic stability. The compound exhibits bench-stable handling, compatibility with common protecting group strategies, and broad functional group tolerance, making it a practical building block for lead optimization and API development.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 3267
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H318
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Precautionary Statements : P264-P270-P280-P330-P501
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Lot numbers can be found on the outside label of a product: