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Structure of 1360921-60-3
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7-Bromo-1H-indole-6-carboxylic acid features a bromine substituent at the 7-position and a carboxylic acid group at the 6-position of the indole core. This configuration enables direct coupling in amide bond formation, supporting efficient access to bioactive scaffolds. The electron-deficient nature of the ring enhances reactivity in transition metal-catalyzed transformations.
7-Bromo-1H-indole-6-carboxylic acid serves as a versatile building block for the synthesis of biologically active indole derivatives. Its bromo and carboxylic acid functionalities enable palladium-catalyzed cross-coupling reactions and direct amidation, facilitating the construction of pharmaceutical scaffolds. The compound exhibits good bench stability and is readily purified by recrystallization, supporting its use in iterative synthetic sequences and API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: