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Structure of 13620-31-0
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2-(Phenylmethoxy)acetonitrile features a benzyl ether linkage and nitrile group, offering a stable, moisture-tolerant handle for conjugate addition reactions. This bifunctional scaffold integrates readily into synthetic sequences requiring selective functionalization under standard conditions.
2-(Phenylmethoxy)acetonitrile serves as a versatile synthetic intermediate for constructing benzyl-protected cyanomethyl motifs. It facilitates nucleophilic additions and subsequent transformations to access β-aryl-substituted nitriles, aldehydes, and carboxylic acid derivatives under mild conditions. The benzyloxy group provides orthogonal protection compatible with standard deprotection protocols, while the nitrile moiety enables diverse functionalization. Its bench-stable nature and ease of purification make it suitable for multi-step synthesis in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: