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Structure of 1362858-88-5
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N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methylalanine is a protected amino acid derivative featuring a fluorenylmethoxycarbonyl (Fmoc) group for orthogonal protection and a methylated α-nitrogen. This configuration enhances stability during peptide synthesis, suppresses racemization, and enables efficient coupling under standard conditions. The sterically hindered N-methyl substitution facilitates selective incorporation into sequences requiring constrained backbone geometry.
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methylalanine serves as a protected amino acid building block for peptide synthesis, enabling efficient incorporation of N-methylated alanine residues. The Fmoc group provides orthogonal protection compatible with standard coupling protocols, while the N-methyl substitution enhances metabolic stability and conformational restriction in bioactive peptides. This derivative exhibits excellent bench stability, simplifies purification, and facilitates high-yielding amide bond formation under common activation conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: