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Structure of 1363380-51-1
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5-Chloro-3-nitropyrazolo[1,5-a]pyrimidine features a fused heterocyclic core with strategically positioned electron-deficient substituents. This combination imparts enhanced reactivity in cross-coupling and nucleophilic substitution processes. The chloro group enables direct functionalization, while the nitro moiety serves as a handle for reduction or displacement. Bench-stable under standard conditions, this scaffold integrates readily into complex molecular architectures.
5-Chloro-3-nitropyrazolo[1,5-a]pyrimidine serves as a versatile heterocyclic building block for medicinal chemistry and agrochemical synthesis. Its chloro and nitro substituents enable selective functionalization via palladium-catalyzed cross-coupling and reduction protocols, respectively. The scaffold exhibits good bench stability and facilitates access to diverse pyrazolopyrimidine derivatives with established utility in kinase inhibitor development and small-molecule library construction.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: