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Structure of 1364663-37-5
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2-Bromo-4-chloro-5-iodopyridine features three halogens positioned for selective cross-coupling reactions. The electron-deficient pyridine core enables efficient Pd-catalyzed transformations, while the orthogonal reactivity of bromo, chloro, and iodo groups permits sequential functionalization. This molecule serves as a key scaffold in medicinal chemistry and materials synthesis, offering precise control over molecular architecture.
2-Bromo-4-chloro-5-iodopyridine serves as a versatile trihalogenated pyridine building block for palladium-catalyzed cross-coupling reactions. Its orthogonal halogen reactivity enables sequential functionalization in complex heterocycle synthesis, particularly in the construction of pharmaceutical scaffolds. The molecule exhibits good bench stability and facilitates efficient coupling with boronic acids, stannanes, and amines under standard conditions, offering predictable regioselectivity and high yields in multistep sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: