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Structure of 13654-62-1
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2-(Ethylsulfonyl)acetonitrile features a dual functional group architecture combining a nitrile and a sulfonylethyl moiety, enabling selective conjugate additions and electrophilic transformations. This bench-stable reagent integrates readily into synthetic sequences requiring polar, electron-withdrawing handles, offering enhanced solubility in common organic solvents and compatibility with diverse reaction conditions.
2-(Ethylsulfonyl)acetonitrile serves as a versatile synthon in medicinal chemistry, enabling the efficient construction of sulfonamide-containing heterocycles and bioactive scaffolds. Its dual functionality—electron-withdrawing nitrile and stable ethylsulfonyl group—facilitates nucleophilic substitution and condensation reactions with high chemoselectivity. The compound exhibits excellent bench stability and compatibility with standard purification methods, making it well-suited for multi-step synthesis and process-scale applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: