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CS-W001157 4
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1,2-Bis[(2R,5R)-2,5-diisopropyl-1-phospholanyl]benzene

  • CAS No. 136705-65-2

  • Cat. No. CS-0106020
  • Molecule weight418.58
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1,2-Bis[(2R,5R)-2,5-diisopropyl-1-phospholanyl]benzene|CS-0106020

Structure of 136705-65-2

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General Information

  • CAS No. 136705-65-2
  • Cat. No. CS-0106020
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₆H₄₄P₂
  • Molecular Weight 418.58
  • Synonym(s) (R,R)-i-Pr-DUPHOS
  • SMILES CC(C)[C@H]1CC[C@H](C(C)C)P1C2=CC=CC=C2P3[C@@H](C(C)C)CC[C@@H]3C(C)C

Description

This chiral diphosphine ligand features two (2R,5R)-2,5-diisopropyl-1-phospholanyl groups attached to a benzene backbone, delivering enhanced steric bulk and electron-donating capacity. Designed for asymmetric catalysis, it stabilizes transition metal complexes under demanding reaction conditions. The rigid scaffold promotes high enantioselectivity in cross-coupling and hydrogenation processes. Bench-stable and moisture-tolerant, it simplifies handling in synthetic workflows.

Synthesis

  • Route1

    References

    • Journal of the American Chemical Society, , vol. 115, # 22 p. 10125 - 10138
  • Route2
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      80510-04-9
    • null|null
      136705-68-5
    • ~%
    • In-stock
      1,2-Bis[(2R,5R)-2,5-diisopropyl-1-phospholanyl]benzene|CS-0106020
      136705-65-2

    References

    • Journal of the American Chemical Society, , vol. 113, # 22 p. 8518 - 8519

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   7.587
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   6

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